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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SETD1B
All Species:
12.73
Human Site:
T652
Identified Species:
21.54
UniProt:
Q9UPS6
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UPS6
NP_055863.1
1923
208732
T652
E
M
P
S
A
P
I
T
S
A
D
C
P
K
P
Chimpanzee
Pan troglodytes
XP_523492
1707
185692
Q629
P
L
G
Y
P
P
H
Q
P
A
Y
L
L
P
P
Rhesus Macaque
Macaca mulatta
XP_001092031
624
66545
Dog
Lupus familis
XP_543382
1925
209302
T654
E
M
P
S
A
P
I
T
S
A
D
C
P
K
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8CFT2
1985
215333
T643
E
M
P
S
A
P
I
T
S
A
D
C
P
K
P
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510235
695
75024
Chicken
Gallus gallus
Q5F3P8
2008
223067
T652
E
M
N
S
A
P
I
T
S
A
E
C
A
K
T
Frog
Xenopus laevis
Q66J90
1938
216239
P662
P
L
P
P
P
P
P
P
Q
S
G
F
P
M
P
Zebra Danio
Brachydanio rerio
Q1LY77
1844
204122
V669
H
L
P
H
H
S
T
V
S
H
L
P
S
H
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001015221
1641
188364
P585
N
N
K
V
L
H
Q
P
N
E
A
S
D
I
S
Honey Bee
Apis mellifera
XP_395451
1406
159180
G351
M
L
L
K
D
K
A
G
G
M
A
P
P
F
L
Nematode Worm
Caenorhab. elegans
Q18221
1507
171664
L452
V
I
R
G
K
N
Q
L
E
N
V
S
S
E
S
Sea Urchin
Strong. purpuratus
XP_791552
1963
220543
P631
H
F
A
K
W
R
C
P
T
L
K
D
Q
E
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q8X0S9
1313
145607
L258
R
L
A
H
G
G
K
L
S
Y
I
N
V
N
F
Conservation
Percent
Protein Identity:
100
37.3
27.9
91.9
N.A.
87.7
N.A.
N.A.
23.1
61.5
55
51
N.A.
24.7
23.9
22.3
21.3
Protein Similarity:
100
50.3
28.8
93.9
N.A.
90.2
N.A.
N.A.
26.7
71.1
66.6
63.6
N.A.
39.4
38.6
35.2
35.2
P-Site Identity:
100
20
0
100
N.A.
100
N.A.
N.A.
0
73.3
26.6
13.3
N.A.
0
6.6
0
0
P-Site Similarity:
100
26.6
0
100
N.A.
100
N.A.
N.A.
0
80
40
20
N.A.
6.6
13.3
13.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
22.2
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
35.4
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
15
0
29
0
8
0
0
36
15
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
8
0
0
0
0
29
0
0
0
% C
% Asp:
0
0
0
0
8
0
0
0
0
0
22
8
8
0
0
% D
% Glu:
29
0
0
0
0
0
0
0
8
8
8
0
0
15
0
% E
% Phe:
0
8
0
0
0
0
0
0
0
0
0
8
0
8
8
% F
% Gly:
0
0
8
8
8
8
0
8
8
0
8
0
0
0
0
% G
% His:
15
0
0
15
8
8
8
0
0
8
0
0
0
8
8
% H
% Ile:
0
8
0
0
0
0
29
0
0
0
8
0
0
8
0
% I
% Lys:
0
0
8
15
8
8
8
0
0
0
8
0
0
29
0
% K
% Leu:
0
36
8
0
8
0
0
15
0
8
8
8
8
0
8
% L
% Met:
8
29
0
0
0
0
0
0
0
8
0
0
0
8
0
% M
% Asn:
8
8
8
0
0
8
0
0
8
8
0
8
0
8
0
% N
% Pro:
15
0
36
8
15
43
8
22
8
0
0
15
36
8
36
% P
% Gln:
0
0
0
0
0
0
15
8
8
0
0
0
8
0
0
% Q
% Arg:
8
0
8
0
0
8
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
29
0
8
0
0
43
8
0
15
15
0
15
% S
% Thr:
0
0
0
0
0
0
8
29
8
0
0
0
0
0
8
% T
% Val:
8
0
0
8
0
0
0
8
0
0
8
0
8
0
8
% V
% Trp:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
0
0
0
8
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _